Urothelial Carcinoma Detection Based on Copy Number Profiles of Urinary Cell-Free DNA by Shallow Whole-Genome Sequencing

Ge, GZ; Peng, D; Guan, B; Zhou, YY; Gong, YQ; Shi, Y; Hao, XY; Xu, ZZ; Qi, J; Lu, H; Zhang, XY; Zhan, YH; Li, YF; Wu, YC; Ding, GP; Shen, Q; He, Q; Li, XS; Zhou, LQ; Ci, WM

Li, XS; Zhou, LQ (corresponding author), Peking Univ, Dept Urol, Hosp 1, 8 St Xishiku, Beijing, Peoples R China.; Li, XS; Zhou, LQ (corresponding author), Peking Univ, Inst Urol, 8 St Xishiku, Beijing, Peoples R China.; Ci, WM (corresponding author), Chinese Acad Sci, Beijing Inst Genom, Bldg 104,1 Beichen West Rd, Beijing, Peoples R China.

CLINICAL CHEMISTRY, 2020; 66 (1): 188

Abstract

BACKGROUND: Current noninvasive assays for urothelial carcinoma (UC) lack clinical sensitivity and specificity. Given the utility of plasma cell-free ......

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