Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis

Chen, JZ; Zhang, S; Cui, P; Shi, WL; Zhang, WH; Zhang, Y

Zhang, Y (reprint author), Fudan Univ, Huashan Hosp, Dept Infect Dis, Key Lab Mol Virol,Inst Med Microbiol, Shanghai, Peoples R China.; Zhang, Y (reprint author), Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 212

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017; 72 (12): 3272

Abstract

Objectives: D-Cycloserine is an important second-line drug used to treat MDR- and XDR-TB. However, the mechanisms of resistance to D-cycloserine are n......

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