Dual FGFR and VEGFR inhibition synergistically restrain hexokinase 2-dependent lymphangiogenesis and immune escape in intrahepatic cholangiocarcinoma

Peng, M; Li, H; Cao, H; Huang, YM; Yu, WP; Shen, CL; Gu, JY

Shen, CL (通讯作者)，Southeast Univ, Med Sch, Dept Microbiol & Immunol, Nanjing 210009, Jiangsu, Peoples R China.;Gu, JY (通讯作者)，Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Liver Transplantat, Wuhan 430022, Peoples R China.;Gu, JY (通讯作者)，Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Transplantat, Shanghai 200092, Peoples R China.

JOURNAL OF GASTROENTEROLOGY, 2023; 58 (9): 908

Abstract

BackgroundTherapies for cholangiocarcinoma are largely limited and ineffective. Herein, we examined the role of the FGF and VEGF pathways in regulatin......

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