An orally available PD-1/PD-L1 blocking peptide OPBP-1-loaded trimethyl chitosan hydrogel for cancer immunotherapy

Li, WQ; Zhu, XQ; Zhou, XM; Wang, XX; Zhai, WJ; Li, BY; Du, JF; Li, GD; Sui, XH; Wu, YH; Zhai, MX; Qi, YM; Chen, GY; Gao, YF

Chen, GY; Gao, YF (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Shenzhen 518107, Peoples R China.

JOURNAL OF CONTROLLED RELEASE, 2021; 334 (): 376

Abstract

Blockade of the immune checkpoint PD-1/PD-L1 with monoclonal antibodies demonstrated unprecedented clinical efficacies in many cancers. But the orally......

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