Sotorasib for Lung Cancers with KRAS p.G12C Mutation

Skoulidis, F; Li, BT; Dy, GK; Price, TJ; Falchook, GS; Wolf, J; Italiano, A; Schuler, M; Borghaei, H; Barlesi, F; Kato, T; Curioni-Fontecedro, A; Sacher, A; Spira, A; Ramalingam, SS; Takahashi, T; Besse, B; Anderson, A; Ang, A; Tran, Q; Mather, O; Henary, H; Ngarmchamnanrith, G; Friberg, G; Velcheti, V; Govindan, R

Skoulidis, F (corresponding author), Univ Texas MD Anderson Canc Ctr, Dept Thorac & Head & Neck Med Oncol, 1515 Holcombe Blvd,Unit 432, Houston, TX 77030 USA.; Govindan, R (corresponding author), Washington Univ, Sch Med, Div Oncol, Alvin J Siteman Canc Ctr,Sec Med Oncol, 660 S Euclid Ave,Box 8056, St Louis, MO 63110 USA.

NEW ENGLAND JOURNAL OF MEDICINE, 2021; 384 (25): 2371

Abstract

BACKGROUND Sotorasib showed anticancer activity in patients with KRAS p.G12C-mutated advanced solid tumors in a phase 1 study, and particularly promis......

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