Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing

Coelho, CH; Nadakal, ST; Hurtado, PG; Morrison, R; Galson, JD; Neal, J; Wu, YM; King, CR; Price, V; Miura, K; Wong-Madden, S; Doritchamou, JYA; Narum, DL; MacDonald, NJ; Snow-Smith, M; Vignali, M; Taylor, JJ; Lefranc, MP; Truck, J; Long, CA; Sagara, I; Fried, M; Duffy, PE

Duffy, PE (corresponding author), NIAID, Lab Malaria Immunol & Vaccinol, NIH, 29 Lincoln Dr, Bethesda, MD 20892 USA.

JCI INSIGHT, 2020; 5 (22):

Abstract

Plasma antimalarial Ab can mediate antiparasite immunity but has not previously been characterized at the molecular level. Here, we develop an innovat......

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