Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions

Fujimaki, M; Furuya, N; Saiki, S; Amo, T; Imamichi, Y; Hattori, N

Furuya, N; Hattori, N (reprint author), Juntendo Univ, Dept Neurol, Sch Med, Tokyo, Japan.; Furuya, N (reprint author), Juntendo Univ, Div Dev Autophagy Modulating Drugs, Grad Sch Med, Tokyo, Japan.

MOLECULAR AND CELLULAR BIOLOGY, 2019; 39 (14):

Abstract

Iron is an essential nutrient for mitochondrial metabolic processes, including mitochondrial respiration. Ferritin complexes store excess iron and pro......

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