Discovery of Highly Specific Catalytic-Site-Targeting Fluorescent Probes for Detecting Lysosomal PDE10A in Living Cells

Gao, YQ; Huang, J; Zhou, Q; Liu, RD; Zhang, SR; Zhang, C; Huang, YY; Li, Z; Huang, L; Wu, DY; Wu, YN; Xiao, LH; Guo, L; Luo, HB

Guo, L; Luo, HB (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Peoples R China.

ACS CHEMICAL BIOLOGY, 2021; 16 (5): 857

Abstract

A challenge for sensors targeting specific enzymes of interest in their native environment for direct imaging is that they rationally exploit a highly......

Full Text Link