Injectable nanofibrous spongy microspheres for NR4A1 plasmid DNA transfection to reverse fibrotic degeneration and support disc regeneration

Feng, GJ; Zhang, ZP; Dang, M; Zhang, XJ; Doleyres, Y; Song, YM; Chen, D; Ma, PX

Ma, PX (reprint author), Univ Michigan, Dept Biol & Mat Sci, 1011 North Univ Ave,Room 2211, Ann Arbor, MI 48109 USA.

BIOMATERIALS, 2017; 131 ( ): 86

Abstract

Safe and efficient gene therapy is highly desired for controlling pathogenic fibrosis of nucleus pulposus (NP) tissue, which would result in intervert......

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