PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis

Zhang, YH; Quick, C; Yu, KT; Barbeira, A; Luca, F; Pique-Regi, R; Im, HK; Wen, XQ

Wen, XQ (corresponding author), Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.

GENOME BIOLOGY, 2020; 21 (1):

Abstract

We propose a new computational framework, probabilistic transcriptome-wide association study (PTWAS), to investigate causal relationships between gene......

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