Re-Engineering RNA Molecules into Therapeutic Agents

Egli, M; Manoharan, M

Egli, M (reprint author), Vanderbilt Univ, Sch Med, Dept Biochem, Nashville, TN 37232 USA.; Manoharan, M (reprint author), Alnylam Pharmaceut, 300 Third St, Cambridge, MA 02142 USA.

ACCOUNTS OF CHEMICAL RESEARCH, 2019; 52 (4): 1036

Abstract

CONSPECTUS: Efforts to chemically modify nucleic acids got underway merely a decade after the discovery of the DNA double helix and initially targeted......

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