Generative modeling of multi-mapping reads with mHi-C advances anal - of Hi-C studies

Zheng, Y; Ay, F; Keles, S

Keles, S (reprint author), Univ Wisconsin, Dept Stat, Madison, WI 53706 USA.; Keles, S (reprint author), Univ Wisconsin, Dept Biostat & Med Informat, Madison, WI 53706 USA.

ELIFE, 2019; 8 ():

Abstract

Current Hi-C analysis approaches are unable to account for reads that align to multiple locations, and hence underestimate biological signal from repe......

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