Specific HER2 Exon 20 Gly776 Deletion-Insertions in Non-Small Cell Lung Cancer: Structural Analysis and Sensitivity to HER2-Targeted Tyrosine Kinase Inhibitors

Yang, GJ; Xu, HY; Hu, JQ; Liu, RZ; Hu, PZ; Yang, YN; Li, WH; Hao, XZ; Zhang, SY; Xu, F; Ai, X; Li, JL; Wang, Y

Wang, Y (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, Dept Med Oncol, Natl Canc Ctr, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China.

FRONTIERS IN PHARMACOLOGY, 2022; 13 ():

Abstract

Background: HER2 exon 20 insertions remain a subset heterogeneous alterations in lung cancer, with currently unmet need for precision targeted therapy......

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