New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development

Ycas, PD; Zahid, H; Chan, A; Olson, NM; Johnson, JA; Talluri, SK; Schonbrunn, E; Pomerantz, WCK

Pomerantz, WCK (corresponding author), Univ Minnesota, Dept Chem, 207 Pleasant St SE, Minneapolis, MN 55455 USA.

ORGANIC & BIOMOLECULAR CHEMISTRY, 2020; 18 (27): 5174

Abstract

Bromodomain-containing proteins regulate transcription through protein-protein interactions with chromatin and serve as scaffolding proteins for recru......

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