Critical role of PAFR/YAP1 positive feedback loop in cardiac fibrosis

Li, TY; Su, W; Li, LL; Zhao, XG; Yang, N; Gai, JX; Lv, X; Zhang, J; Huang, MQ; Zhang, Q; Ji, WH; Song, XY; Zhou, YH; Li, XL; Shan, HL; Liang, HH

Liang, HH (通讯作者),Harbin Med Univ, Coll Pharm, Dept Pharmacol,Minist Educ, Key Lab Cardiovasc Res,State Prov Key Labs Biomed, Harbin 150081, Peoples R China.;Shan, HL (通讯作者),Shanghai Univ Engn Sci, Shanghai Frontiers Sci Res Ctr Druggabil Cardiova, Inst Frontier Med Technol, Shanghai 201620, Peoples R China.;Liang, HH (通讯作者),Chinese Acad Med Sci, Res Unit Noninfect Chron Dis Frigid Zone 2019RU07, Harbin 150081, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2022; 43 (11): 2862

Abstract

Aberrant activation of cardiac fibroblasts is the main cause and character of cardiac fibrosis, and inhibition of cardiac fibrosis becomes a promising......

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