Loops D, E and G in the Drosophila D1 subunit contribute to high neonicotinoid sensitivity of D1-chicken 2 nicotinic acetylcholine receptor

Ihara, M; Hikida, M; Matsushita, H; Yamanaka, K; Kishimoto, Y; Kubo, K; Watanabe, S; Sakamoto, M; Matsui, K; Yamaguchi, A; Okuhara, D; Furutani, S; Sattelle, DB; Matsuda, K

Matsuda, K (reprint author), Kindai Univ, Dept Appl Biol Chem, Fac Agr, 3327-204 Nakamachi, Nara 6318505, Japan.

BRITISH JOURNAL OF PHARMACOLOGY, 2018; 175 (11): 1999

Abstract

Background and PurposeNeonicotinoid insecticides interact with the orthosteric site formed at subunit interfaces of insect nicotinic ACh (nACh) recept......

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