High lumenal chloride in the lysosome is critical for lysosome function

Chakraborty, K; Leung, K; Krishnan, Y

Krishnan, Y (reprint author), Univ Chicago, Dept Chem, 5735 S Ellis Ave, Chicago, IL 60637 USA.; Krishnan, Y (reprint author), Univ Chicago, Grossman Inst Neurosci Quantitat Biol & Human Beh, Chicago, IL 60637 USA.

ELIFE, 2017; 6 ( ):

Abstract

Lysosomes are organelles responsible for the breakdown and recycling of cellular machinery. Dysfunctional lysosomes give rise to lysosomal storage dis......

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