RAR gamma activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway

Wang, Q; Lin, ZJ; Wang, Z; Ye, LQ; Xian, M; Xiao, LL; Su, P; Bi, EG; Huang, YH; Qian, JF; Liu, LT; Ma, XZ; Yang, MJ; Xiong, W; Zu, YL; Pingali, SR; Xu, B; Yi, Q

Xu, B (通讯作者)，Xiamen Univ, Dept Hematol, Affiliated Hosp 1, Xiamen, Fujian, Peoples R China.;Yi, Q (通讯作者)，Houston Methodist Res Inst, Houston Methodist Canc Ctr, Canc Ctr, Ctr Translat Res Hematol Malignancies, Houston, TX 77030 USA.

BLOOD, 2022; 139 (1): 59

Abstract

Proteasome inhibitors (Pis) such as bortezomib (Btz) and carfilzomib (Cfz) are highly efficacious for patients with multiple myeloma (MM). However, re......

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