Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis

Li, TW; Peng, R; Wang, F; Hua, L; Liu, S; Han, ZY; Pei, JQ; Pei, SQ; Zhao, ZW; Jiang, X; Chen, X

Chen, X (corresponding author), Chinese Acad Med Sci, State Key Lab Cardiovasc Dis, Peking Union Med Coll, Natl Ctr Cardiovasc Dis,Fuwai Hosp,Diagnost Lab S, Beijing, Peoples R China.; Jiang, X (corresponding author), Chinese Acad Med Sci, Peking Union Med Coll Hosp, Key Lab Pulm Vasc Med, Dept Cardiol, Beijing, Peoples R China.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020; 18 (8): 1952

Abstract

Background Lysophosphatidic acid (LPA), a bioactive phospholipid released by activated platelets, can induce platelet shape changes and aggregation, w......

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