Overexpression of HIF-1 alpha contributes to melphalan resistance in multiple myeloma cells by activation of ERK1/2, Akt, and NF-kappa B

Tsubaki, M; Takeda, T; Tomonari, Y; Koumoto, Y; Imano, M; Satou, T; Nishida, S

Nishida, S (reprint author), Kindai Univ, Fac Pharm, Div Pharmacotherapy, Higashiosaka, Osaka, Japan.

LABORATORY INVESTIGATION, 2019; 99 (1): 72

Abstract

Multiple myeloma (MM) commonly displays multidrug resistance and is associated with poor prognosis. Therefore, it is important to identify the mechani......

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