Genetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the Heart

Man, JCK; van Duijvenboden, K; Krijger, PHL; Hooijkaas, IB; van der Made, I; de Gier-de Vries, C; Wakker, V; Creemers, EE; de Laat, W; Boukens, BJ; Christoffels, VM

Christoffels, VM (corresponding author), Univ Amsterdam, Dept Med Biol, Amsterdam UMC, Amsterdam Cardiovasc Sci, Meibergdreef 15, NL-1105 AZ Amsterdam, Netherlands.

CIRCULATION RESEARCH, 2021; 128 (1): 115

Abstract

Rationale: ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide), encoded by the clustered genes Nppa and Nppb, are important prognost......

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