A Robust and Scalable Process for the Synthesis of Substantially Pure Clarithromycin 9-(E)-Oxime with an Established Control of the (Z)-Isomer Impurity

Chaudhari, K; Gohar, A; Claerhout, S; Ganorkar, R

Chaudhari, K (通讯作者),Hikal Ltd, Pune 411057, Maharashtra, India.

ACS OMEGA, 2023; 8 (11): 10411

Abstract

Controlling the isomeric impurity in a key raw material is always critical to achieve the corresponding pure isomer-free targeted active pharmaceutica......

Full Text Link