Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma

Li, DY; Yao, YC; Rao, YH; Huang, XY; Wei, L; You, ZM; Zheng, G; Hou, XL; Su, Y; Varghese, Z; Moorhead, JF; Chen, YX; Ruan, XZ

Chen, YX; Ruan, XZ (通讯作者)，Chongqing Med Univ, Ctr Lipid Res, Inst Viral Hepatitis, Dept Infect Dis,Affiliated Hosp 2,Minist Educ, Chongqing 400016, Peoples R China.;Chen, YX; Ruan, XZ (通讯作者)，Chongqing Med Univ, Res & Key Lab Mol Biol Infect Dis, Inst Viral Hepatitis, Dept Infect Dis,Affiliated Hosp 2,Minist Educ, Chongqing 400016, Peoples R China.;Ruan, XZ (通讯作者)，UCL, John Moorhead Res Lab, Ctr Nephrol, Med Sch, London NW3 2PF, England.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2022; 41 (1):

Abstract

Background Hepatocellular carcinoma (HCC) is one of the most malignant tumors and the fourth leading cause of cancer-related death worldwide. Sorafeni......

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