The NAD(+) precursor NMN activates dSarm to trigger axon degeneration in Drosophila

Rosell, AL; Paglione, M; Gilley, J; Kocia, M; Perillo, G; Gasparrini, M; Cialabrini, L; Raffaelli, N; Angeletti, C; Orsomando, G; Wu, PH; Coleman, MP; Loreto, A; Neukomm, LJ

Neukomm, LJ (通讯作者),Univ Lausanne, Dept Fundamental Neurosci, Lausanne, Switzerland.

ELIFE, 2022; 11 ():

Abstract

Axon degeneration contributes to the disruption of neuronal circuit function in diseased and injured nervous systems. Severed axons degenerate followi......

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