Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood

Fujimoto, M; Khoury, JC; Khoury, PR; Kalra, B; Kumar, A; Sluss, P; Oxvig, C; Hwa, V; Dauber, A

Dauber, A (corresponding author), Univ Cincinnati, Coll Med, Cincinnati Childrens Hosp Med Ctr, Cincinnati Ctr Growth Disorders,Div Endocrinol, Cincinnati, OH 45221 USA.; Dauber, A (corresponding author), Childrens Natl Hosp, Div Endocrinol, Washington, DC 20010 USA.; Dauber, A (corresponding author), George Washington Univ, Sch Med & Hlth Sci, Dept Pediat, Washington, DC 20052 USA.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2020; 182 (3): 363

Abstract

Objective: Pregnancy-associated plasma protein-A2 (PAPP-A2) is a metalloproteinase that cleaves IGFBP-3 and IGFBP-5. Human mutations in PAPPA2 result ......

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