Investigating the Unbinding of Muscarinic Antagonists from the Muscarinic 3 Receptor

Buigues, PJ; Gehrke, S; Badaoui, M; Dudas, B; Mandana, G; Qi, TY; Bottegoni, G; Rosta, E

Rosta, E (通讯作者),UCL, Dept Phys & Astron, London WC1E 6BT, England.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2023; 19 (15): 5260

Abstract

Patient symptom relief is often heavily influenced bythe residencetime of the inhibitor-target complex. For the human muscarinicreceptor 3 (hMR3), tio......

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