BMPR2 inhibits activin and BMP signaling via wild-type ALK2

Olsen, OE; Sankar, M; Elsaadi, S; Hella, H; Buene, G; Darvekar, SR; Misund, K; Katagiri, T; Knaus, P; Holien, T

Holien, T (reprint author), NTNU Norwegian Univ Sci & Technol, Dept Clin & Mol Med, N-7491 Trondheim, Norway.; Holien, T (reprint author), St Olavs Univ Hosp, Dept Hematol, N-7030 Trondheim, Norway.

JOURNAL OF CELL SCIENCE, 2018; 131 (11):

Abstract

TGF-beta/BMP superfamily ligands require heteromeric complexes of type 1 and 2 receptors for ligand-dependent downstream signaling. Activin A, a TGF-b......

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