A carvedilol analogue, VK-II-86, prevents hypokalaemia-induced ventricular arrhythmia through novel multi-channel effects

Robinson, VM; Alsalahat, I; Freeman, S; Antzelevitch, C; Barajas-Martinez, H; Venetucci, L

Robinson, VM (通讯作者)，Univ Manchester, Div Cardiovasc Sci, Fac Biol Med & Hlth, Core Technol Facil, 3rd Floor,46 Grafton St, Manchester M13 9WU, Lancs, England.

BRITISH JOURNAL OF PHARMACOLOGY, 2022; 179 (11): 2713

Abstract

Background and Purpose QT prolongation and intracellular Ca2+ loading with diastolic Ca2+ release via ryanodine receptors (RyR2) are the predominant m......

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