Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

Côrte-Real, BF; Hamad, I; Hornero, RA; Geisberger, S; Roels, J; Van Zeebroeck, L; Dyczko, A; van Gisbergen, MW; Kurniawan, H; Wagner, A; Yoset, N; Weiss, SNY; Schmetterer, KG; Schröder, A; Krampert, L; Haase, S; Bartolomaeus, H; Hellings, N; Saeys, Y; Dubois, LJ; Brenner, D; Kempa, S; Hafler, DA; Stegbauer, J; Linker, RA; Jantsch, J; Müller, DN; Kleinewietfeld, M

Kleinewietfeld, M (通讯作者)，Hasselt Univ, VIB Ctr Inflammat Res IRC, VIB Lab Translat Immunomodulat, B-3590 Diepenbeek, Belgium.;Kleinewietfeld, M (通讯作者)，Hasselt Univ, Biomed Res Inst, Dept Immunol, B-3590 Diepenbeek, Belgium.

CELL METABOLISM, 2023; 35 (2): 299

Abstract

FOXP3+ regulatory T cells (Tregs) are central for peripheral tolerance, and their deregulation is associated with autoimmunity. Dysfunctional autoimmu......

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