The TLR7/IRF-5 axis sensitizes memory CD4+T cells to Fas-mediated apoptosis during HIV-1 infection

Carmona-Pérez, L; Dagenais-Lussier, X; Mai, LT; Stögerer, T; Swaminathan, S; Isnard, S; Rice, MR; Barnes, BJ; Routy, JP; van Grevenynghe, J; Stäger, S

Stäger, S (通讯作者)，INRS Ctr Armand Frappier Sante Biotechnol, 531 Blvd Prairies, Laval, PQ H7V 1B7, Canada.

JCI INSIGHT, 2023; 8 (13):

Abstract

HIV-1 infection is characterized by inflammation and a progressive decline in CD4+ T cell count. Despite treatment with antiretroviral therapy (ART), ......

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