Distinct impact of IgG subclass on autoantibody pathogenicity in different IgG4-mediated diseases

Bi, YX; Su, J; Zhou, SR; Zhao, YJ; Zhang, Y; Zhang, HH; Liu, MD; Zhou, AW; Xu, JR; Pan, M; Zhao, YM; Li, FB

Li, FB (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Ctr Immune Related Dis Shanghai Inst Immunol, Shanghai, Peoples R China.;Li, FB (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China.;Zhao, YM (通讯作者)，Soochow Univ, Affiliated Hosp 1, Jiangsu Inst Hematol, Suzhou, Peoples R China.;Zhao, YM (通讯作者)，Soochow Univ, Collaborat Innovat Ctr Hematol, Suzhou, Peoples R China.;Pan, M (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Dept Dermatol, Shanghai, Peoples R China.

ELIFE, 2022; 11 ():

Abstract

IgG4 is the least potent human IgG subclass for the Fc gamma R-mediated antibody effector function. Paradoxically, IgG4 is also the dominant IgG subcl......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索