Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells

Poreba, M; Rut, W; Groborz, K; Snipas, SJ; Salvesen, GS; Drag, M

Poreba, M; Drag, M (reprint author), Sanford Burnham Prebys Med Discovery Inst, NCI Designated Canc Ctr, 10901 North Torrey Pines Rd, La Jolla, CA 92037 USA.; Poreba, M; Drag, M (reprint author), Wroclaw Univ Sci & Technol, Fac Chem, Dept Bioorgan Chem, W

CELL DEATH AND DIFFERENTIATION, 2019; 26 (12): 2695

Abstract

Most caspases can be positioned unambiguously within the regulated cell death networks of apoptosis and pyroptosis, but the role of caspase-2, a highl......

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