Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages

Palmer, C; Facchini, FA; Jones, RPO; Neumann, F; Peri, F; Pirianov, G

Pirianov, G (corresponding author), Anglia Ruskin Univ, Sch Life Sci, East Rd, Cambridge CB1 1PT, England.

INNATE IMMUNITY, 2021; 27 (3): 275

Abstract

TLRs, including TLR4, play a crucial role in inflammatory-based diseases, and TLR4 has been identified as a therapeutic target for pharmacological int......

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