Histopathologic Characterization of Mifepristone-induced Ovarian Toxicity in Cynomolgus Monkeys

Taketa, Y; Horie, K; Goto, T; Ohta, E; Nakano-Ito, K; Hayakawa, K; Seki, Y; Goto, A; Hosokawa, S

Taketa, Y (reprint author), Eisai & Co Ltd, Tsukuba Drug Safety, Global Drug Safety, Biopharmaceut Assessments Core Funct Unit, 5-1-3 Tokodai, Tsukuba, Ibaraki 3002635, Japan.

TOXICOLOGIC PATHOLOGY, 2018; 46 (3): 283

Abstract

Mifepristone, which is an orally active synthetic steroid with antiprogesterone activity, is known as an ovarian toxicant. Because the available data ......

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