TDP-43 shapeshifts to encipher FTD severity

Barbieri, EM; Shorter, J

Shorter, J (reprint author), Univ Penn, Dept Biochem & Biophys, Perelman Sch Med, Philadelphia, PA 19104 USA.

NATURE NEUROSCIENCE, 2019; 22 (1): 3

Abstract

TDP-43 forms cytoplasmic aggregates in degenerating neurons of frontotemporal dementia (FTD) patients. Laferriere et al. now establish that TDP-43 ass......

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