Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization

He, Y; Li, K; Cao, YM; Sun, ZX; Li, PH; Bao, HF; Wang, S; Zhu, GQ; Bai, XW; Sun, P; Liu, XR; Yang, C; Liu, ZX; Lu, ZJ; Rao, ZH; Lou, ZY

Rao, ZH (corresponding author), Nankai Univ, Coll Pharm, State Key Lab Med Chem Biol, Tianjin, Peoples R China.; Rao, ZH (corresponding author), Nankai Univ, Coll Pharm, Drug Discovery Ctr Infect Dis, Tianjin, Peoples R China.; Rao, ZH; Lou, ZY (corresponding author), Tsinghua Univ, MOE Key Lab Prot Sci, Beijing, Peoples R China.; Rao, ZH; Lou, ZY (corresponding author), Tsinghua Univ, Collaborat Innovat Ctr Biotherapy, Sch Med, Beijing, Peoples R China.; Rao, ZH; Lou, ZY (corresponding author),

PLOS PATHOGENS, 2021; 17 (4):

Abstract

The development of a universal vaccine against foot-and-mouth disease virus (FMDV) is hindered by cross-serotype antigenic diversity and by a lack of ......

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