Genetic and epigenetic study of an Alzheimer's disease family with monozygotic triplets

Zhang, M; Dilliott, AA; Khallaf, R; Robinson, JF; Hegele, RA; Comishen, M; Sato, C; Tosto, G; Reitz, C; Mayeux, R; St George-Hyslop, P; Freedman, M; Rogaeva, E

Rogaeva, E (reprint author), Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, 60 Leonard Ave, Toronto, ON M5T 0S8, Canada.; Freedman, M (reprint author), Baycrest Hlth Sci, Rotman Res Inst, Toronto, ON, Canada.

BRAIN, 2019; 142 (): 3375

Abstract

Age at onset of Alzheimer's disease is highly variable, and its modifiers (genetic or environmental) could act through epigenetic changes, such as DNA......

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