The structure of MgtE in the absence of magnesium provides new insights into channel gating

Jin, F; Sun, MX; Fujii, T; Yamada, Y; Wang, J; Maturana, AD; Wada, M; Su, SC; Ma, JB; Takeda, H; Kusakizako, T; Tomita, A; Nakada-Nakura, Y; Liu, KH; Uemura, T; Nomura, Y; Nomura, N; Ito, K; Nureki, O; Namba, K; Iwata, S; Yu, Y; Hattori, M

Hattori, M (corresponding author), Fudan Univ, State Key Lab Genet Engn, Collaborat Innovat Ctr Genet & Dev,Sch Life Sci, Shanghai Key Lab Bioact Small Mol,Dept Physiol &, Shanghai, Peoples R China.

PLOS BIOLOGY, 2021; 19 (4):

Abstract

MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasi......

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