A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing

Jones, EM; Jajoo, R; Cancilla, D; Lubock, NB; Wang, J; Satyadi, M; Cheung, R; de March, C; Bloom, JS; Matsunami, H; Kosuri, S

Kosuri, S (reprint author), Univ Calif Los Angeles, Eli & Edythe Brd Ctr Regenerat Med & Stem Cell Re, US DOE,Inst Genom & Prote, Mol Biol Inst,Quantitat & Computat Biol Inst,Dept, Los Angeles, CA 90095 USA.; Kosuri, S (reprint author), Univ Calif Los Ang

CELL SYSTEMS, 2019; 8 (3): 254

Abstract

G protein-coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the larges......

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