SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function

Hu, ZL; Teng, XL; Zhang, TY; Yu, XY; Ding, R; Yi, J; Deng, LF; Wang, ZT; Zou, Q

Deng, LF; Zou, Q (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Shanghai Inst Immunol, Dept Immunol & Microbiol,State Key Lab Oncogenes, 280 South Chongqing Rd, Shanghai 200025, Peoples R China.; Wang, ZT (corresponding author), Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Gastroenterol, Sch Med, Shanghai 200025, Peoples R China.

MOLECULAR CELL, 2021; 81 (5): 940

Abstract

STING-dependent cytosolic DNA sensing in dendritic cells (DCs) initiates antitumor immune responses, but how STING signaling is metabolically regulate......

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