SGLT2 inhibitor dapagliflozin attenuates cardiac fibrosis and inflammation by reverting the HIF-2 alpha signaling pathway in arrhythmogenic cardiomyopathy

Yang, Z; Li, TL; Xian, JZ; Chen, J; Huang, Y; Zhang, Q; Lin, XF; Lu, HY; Lin, YB

Lin, YB (通讯作者)，Guangdong Med Univ, Dongguan Affiliated Hosp 1, Dongguan 523710, Peoples R China.;Lu, HY (通讯作者)，Jinan Univ, Zhuhai Hosp, Dept Endocrinol & Metab, Zhuhai 519000, Guangdong, Peoples R China.

FASEB JOURNAL, 2022; 36 (7):

Abstract

Excessive cardiac fibrosis and inflammation aberrantly contribute to the progressive pathogenesis of arrhythmogenic cardiomyopathy (ACM). Whether sodi......

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