Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

Patterson, JC; Varkaris, A; Croucher, PJP; Ridinger, M; Dalrymple, S; Nouri, M; Xie, F; Varmeh, S; Jonas, O; Whitman, MA; Chen, S; Rashed, S; Makusha, L; Luo, J; Isaacs, JT; Erlander, MG; Einstein, DJ; Balk, SP; Yaffe, MB

Yaffe, MB (通讯作者)，Koch Inst Integrat Canc Biol, MIT, Dept Biol & Biol Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA.

CANCER RESEARCH, 2023; 83 (2): 219

Abstract

Abiraterone is a standard treatment for metastatic castrate-resistant prostate cancer (mCRPC) that slows disease progression by abrogating androgen sy......

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