Pitavastatin stimulates retinal angiogenesis via HMG-CoA reductase-independent activation of RhoA-mediated pathways and focal adhesion

Li, Z; Zhang, J; Xue, YN; He, Y; Tang, LL; Ke, M; Gong, Y

Ke, M (corresponding author), Wuhan Univ, Dept Ophthalmol, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.; Gong, Y (corresponding author), Wuhan Univ, Dept Biol Repositories, Zhongnan Hosp, 169 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2021; 259 (9): 2707

Abstract

Background Excessive angiogenesis of the retina is a key component of irreversible causes of blindness in many ocular diseases. Pitavastatin is a chol......

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