Randomized phase III trial of S-1 versus capecitabine in the first-line treatment of metastatic colorectal cancer: SALTO study by the Dutch Colorectal Cancer Group

Kwakman, JJM; Simkens, LHJ; van Rooijen, JM; van de Wouw, AJ; ten Tije, AJ; Creemers, GJM; Hendriks, MP; Los, M; van Alphen, RJ; Polee, MB; Muller, EW; van der Velden, AMT; van Voorthuizen, T; Koopman, M; Mol, L; van Werkhoven, E; Punt, CJA

Punt, CJA (reprint author), Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands.

ANNALS OF ONCOLOGY, 2017; 28 (6): 1288

Abstract

Background: Hand-foot syndrome (HFS) is a common side-effect of capecitabine. S-1 is an oral fluoropyrimidine with comparable efficacy to capecitabine......

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