The cytoplasmic region of the amyloid beta-protein precursor (APP) is necessary and sufficient for the enhanced fast velocity of APP transport by kinesin-1

Tsukamoto, M; Chiba, K; Sobu, Y; Shiraki, Y; Okumura, Y; Hata, S; Kitamura, A; Nakaya, T; Uchida, S; Kinjo, M; Taru, H; Suzuki, T

Suzuki, T (reprint author), Hokkaido Univ, Grad Sch Pharmaceut Sci, Lab Neurosci, Kita Ku, Kita 12 Nishi 6, Sapporo, Hokkaido 0600812, Japan.

FEBS LETTERS, 2018; 592 (16): 2716

Abstract

Amyloid beta-protein precursor (APP) is transported mainly by kinesin-1 and at a higher velocity than other kinesin-1 cargos, such as Alcadein alpha (......

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