Pharmacology of JNJ-28583113: A novel TRPM2 antagonist

Fourgeaud, L; Dvorak, C; Faouzi, M; Starkus, J; Sandeo, S; Wang, Q; Lord, B; Coate, H; Taylor, N; He, YB; Qin, N; Wickenden, A; Carruthers, N; Lovenberg, TW; Penner, R; Bhattacharya, A

Fourgeaud, L (reprint author), Janssen Res & Dev LLC, 3210 Merryfield Row, San Diego, CA 92121 USA.

EUROPEAN JOURNAL OF PHARMACOLOGY, 2019; 853 (): 299

Abstract

Transient receptor potential melastatin type 2 (TRPM2) is a cation channel activated by free intracellular AD-Pribose and reactive oxygen species. TRP......

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