Irradiated lactic acid-stimulated tumour cells promote the antitumour immunity as a therapeutic vaccine

Yu, JY; Shao, B; Luo, M; Du, W; Nie, W; Yang, JY; Wei, XW

Wei, XW (corresponding author), Sichuan Univ, West China Hosp, Natl Clin Res Ctr Geriatr,Lab Aging Res & Canc Dr, State Key Lab Biotherapy, 17 Block 3,Southern Renmin Rd, Chengdu 610041, Sichuan, Peoples R China.; Wei, XW (corresponding author), Sichuan Univ, West China Hosp, Natl Clin Res Ctr Geriatr, Canc Ctr, 17 Block 3,Southern Renmin Rd, Chengdu 610041, Sichuan, Peoples R China.

CANCER LETTERS, 2020; 469 (): 367

Abstract

Low pH and lactate accumulation are characteristic features of the tumour microenvironment. With our study finding that high concentrations of lactic ......

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