Consequences of HLA-associated mutations in HIV-1 subtype C Nef on HLA-I downregulation ability

Mann, JK; Rajkoomar, E; Jin, SW; Mkhize, Q; Baiyegunhi, O; Mbona, P; Brockman, MA; Ndung'u, T

Ndung'u, T (corresponding author), Univ KwaZulu Natal, HIV Pathogenesis Programme, 719 Umbilo Rd, ZA-4013 Durban, South Africa.

JOURNAL OF MEDICAL VIROLOGY, 2020; 92 (8): 1182

Abstract

Identification of CD8+ T lymphocyte (CTL) escape mutations that compromise the pathogenic functions of the Nef protein may be relevant for an HIV-1 at......

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