Sci-Hi-C: A single-cell Hi-C method for mapping 3D genome organization in large number of single cells

Ramani, V; Deng, XX; Qiu, RL; Lee, C; Disteche, CM; Noble, WS; Shendure, J; Duan, ZJ

Ramani, V; Shendure, J (corresponding author), Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA.; Duan, ZJ (corresponding author), Univ Washington, Sch Med, Div Hematol, Seattle, WA 98195 USA.

METHODS, 2020; 170 (): 61

Abstract

The highly dynamic nature of chromosome conformation and three-dimensional (3D) genome organization leads to cell-to-cell variability in chromatin int......

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