GC bias affects genomic and metagenomic reconstructions, underrepresenting GC-poor organisms

Browne, PD; Nielsen, TK; Kot, W; Aggerholm, A; Gilbert, MTP; Puetz, L; Rasmussen, M; Zervas, A; Hansen, LH

Browne, PD; Hansen, LH (corresponding author), Univ Copenhagen, Dept Plant & Environm Sci, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark.

GIGASCIENCE, 2020; 9 (2):

Abstract

Background: Metagenomic sequencing is a well-established tool in the modern biosciences. While it promises unparalleled insights into the genetic cont......

Full Text Link